Precise engineering and visualization of signs and magnitudes of DNA writhe on the basis of PNA invasion.
نویسندگان
چکیده
It is demonstrated that the right and left handedness of DNA supercoils can be engineered precisely and readily at the molecular level in vitro through utilization of the invading property of peptide nucleic acid.
منابع مشابه
Invasion Percolation in Presence of Gravity
Simultaneous capillary dominated displacement of the wetting and non-wetting phases are processes of interest in many disciplines including modeling of the penetration of polluting liquids in hydrology or the secondary migration in petroleum reservoir engineering. Percolation models and in particular invasion percolation is well suited to characterize the slow immiscible displaceme...
متن کاملDesign of Air Distribution System for Operation Theatre Using Flow Visualization Techniques to Improve Flow Characteristics
Operation Theatre (OT) is the most important area where precise controlled on indoor air quality is required because it is directly related to patient health and its recovery period. This work aims to study and visualize the airflow distribution of conventional flat air diffuser ventilation system and newly designed angular air ventilation system in OT. Angular Air Distribution (AAD) system is ...
متن کاملCellular Morphology and Immunologic Properties of Escherichia coli Treated With Antimicrobial Antisense Peptide Nucleic Acid
Background & Objectives: Antisense peptide nucleic acids (PNA) that target growth essential genes show potent bactericidal properties without cell lysis. We considered the possibility that whether PNA treatment influence the bacteria total nucleic acids content and apply approach to develop a new delivery system to Dendritic cells (DCs). DCs are the most potent antigen presenting cells in th...
متن کاملRe-usability of traffic signs for inactive drivers with consideration of personal characteristics and sign features
There has been an increasing concern about inactive drivers who would easily lead to road accidents and fatalities once return to driving. This study investigated the re-usability of traffic signs for inactive drivers with consideration of driver factors and cognitive sign features. Fifty-seven Hong Kong Chinese, who possessed a full driving license but had not driven for an extended period, co...
متن کاملManipulating DNA writhe through varying DNA sequences.
It is demonstrated that the shapes and magnitudes of DNA writhe can be precisely manipulated solely through maneuvering the nucleotide sequence of DNA and without the assistance of topoisomerases.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Chemical communications
دوره 47 38 شماره
صفحات -
تاریخ انتشار 2011